Targeted Radiochemistry and Associated Technology Development for Integrated Nuclear Medicine Research and Training with Human Application: A Joint Research Funding Opportunity Announcement NIH, DOE

The U.S. Department of Energy's Office of Science, Office of Biological and Environmental Research (OBER), and the National Institutes of Health (NIH), National Institute of Biomedical Imaging and Bioengineering (NIBIB), hereby announce their interest in receiving applications for potential funding of Translational Biomarkers Development to serve two important goals: 1. Develop clinically relevant radionuclide imaging biomarkers to individualize and optimize medical care through new, improved diagnostic and theranostic approaches, and 2. Enhancement of training opportunities of young scientists and clinicians in translational nuclear medicine. Applicants must have access to existing advanced facilities and an interdisciplinary collaborative team of clinicians specialized in human disease- or disorder-specific nuclear medicine imaging techniques as well as radiochemists, synthetic chemists, and/or biochemists with the ability to support a robust research-training environment. Institutional settings should offer broad ranging research collaborations between clinical physicians and basic and translational research scientists. In addition, research applicants should have easy access to advanced nuclear medicine imaging facilities, such as positron emission tomography (PET) and single photon emission computed tomography (SPECT), and radiochemistry laboratories for radiotracer synthesis, validation and quality control.