Biologically-derived Medicines on Demand (Bio-MOD)

The Bio-MOD program seeks to develop devices and techniques to produce multiple protein biologics in response to specific battlefield threats and medical needs. This will be achieved by investing in (1) novel, flexible methodologies for genetic engineering/modification of microbial strains, eukaryotic strains, and/or cell-free systems to synthesize multiple protein-based therapeutics; and (2) flexible and portable device platforms for manufacturing multiple biologics with high purity, efficacy and potency at the point-of-care, in short timeframes, when the specific need arises. Consequently, Bio-MOD will provide a battlefield medical supply for military medics at the front lines of support that is responsive to far-forward emergency settings and emergent in-theater needs.