SOURCES SOUGHT NOTICE For the MEA (Multi-electrode 2100 System) Brand Name or Equal The Research & Development Service at the Atlanta VA Medical Center, 1670 Clairmont Road, Decatur GA 30033 has a requirement for the purchase of the following Brand Name or Equal MEA ( Multielectrode array) MEA2100-System, Zaiz Axio Observer 5, and supporting accessories. DESCRIPTION QUANTITY UNIT MEA(Multielectrode) 2100-SYSTEM 1 EA SYSTEM ACCESSORIES SEE BELOW EA ZAIZ AXIO OBSERVER 5 1 EA 1- MEA2100 SYSTEM FOR TWO 60 ELECTRODE MEA WITH PERFUSION CANNULA 1- PERFUSION ELEMENTS FOR MEA2100 HEADSTAGE 1- ADDITIONAL RECEIVER FOR WIRELESS2100 SYSTEM 5- ADDITIONAL RECEIVER FOR WIRELESS2100 SYSTEM 2- W2100 C CHARGING DEVICE FOR BATTERY OF W2100 HEADSTAGES 10- BATTERY FOR WIRELESS HEADSTAGE FOR W2100 SYSTEM (100 MAH) 1- CLEANBENCH 30X36 INCH THREAD 1- CASTERS, SET OF 4 1- FARADAY CAGE F/TBL 76.2x 91.4cm 30x36"W/ROLL UP DOOR NO BASEPLATE W/THIS MODEL. REQUIRES PERIMETER ENCLOSURE (ORDER SEPARATELY) TO ATTACH TO ISOLATION TABLE. 1- PERIMETER CLEANBENCH 30X36 2- COMPLETE PERFUSION VALVE CONTROL SYSTEM WITH PINCH VALVES 8 CHANNEL 1- Axio Observer 5 MISC CHARGES 1- Sideport 60N L 100/100 2 pos f/Observer 1- Mirror Insert VIS f/BaseSlider f/Vert200 1- Optovar Mount 1 Position Fixed 1- Z drive Operation Flat Left Imgr/Obsrvr 1- Illum Carrier Tilt Back LCD f/ObserverD1 1- Illuminator microLED 1- Phosphorescence block filter for LED transmitted light illumination 1- Interface f/ 0.55 Mot Condsr & Shutter 1- Binoc Tube 45/23 f/ Axio Observer 2- Eyepiece PL 10x/23 Br foc 2- Folding Eyecup 1- Condsr LD 0.55 H/DIC/Ph1/Ph2/Ph3/Var1/2 1- Auxiliary microscope d=30 1- FL/HD Light Train Man UV f/Observer with extended UV transmission for future possible upgrade to Fura 2 Imaging 1- Diaphragm Slider f/Vert200 & Observer 1- Shutter FL, Internal f/ Observer D1 Z1 Fluorescence Filter Reflector Turret 6x Motorized f/ Observer 1-Glass Cover for FL Turret 1-X Cite 120 LED Boost System 1- Reflector Module FL EC P&C 1- FL Filter Set 49 DAPI,EX G365 S free 1- FL Filter Set 10,ExBP450 490 ShiftFree 1- FL Filter Set 38 HE GFP shift free 1- FL Filter Set 50 Cy5, EX BP640/30 S free 1- STAGE ZEISS AXIO VERT INCH 1- LD A Plan 10x/0.25 Ph1 (PS) 1- LD A Plan 5x/0,15 Ph1 1-LD A Plan 20x/0.35 Ph1 1- LD A Plan 40x/0.55 Ph2 1- EC Plan Neofluar 100x/1.3 Oil WD=0.2 M27 1-Axiocam 506 Mono and 0.63x C Mount 1- ZEN 2.3 pro 2012 US Hardware License Key 1- Workstation Compact ZEISS 60BC 1- Memory 16 GB (1x16) DDR4 2133 (Z240) 1- Solid State Drive SSD 256 GB M.2 1- Monitor TFT 27"HP Z27n 10- MICROELECTRODE ARRAY PERFORATED LAYOUT 5- 6 WELL MICROELECTRODE ARRAY 5-WIRELESS HEADSTAGE WITH 4 RECORDING CHANNELS WITH INTERFACE FOR OPTICAL STIM 2-CLIMATE CHAMBER FOR MEA2100 SYSTEMS SALIENT CHARACTERISTICS: ****This equipment will NOT be connected to the VA network**** The MEA system Rats & Mice must perform the following functions: Multielectrode recording for over 100 cells simultaneously in neuronal cultures. Cell membrane activities and action potentials are collected and analyzed by a PC computer for neuronal activity, synaptic connections and regulations by physical, molecular and chemical manipulations. Multielectrode recording for up to 60 locations simultaneously in brain spaces. Field membrane potential and evoked spikes are collected and analyzed by a PC computer for neuronal connections, neural pathways, synaptic transmission/plasticity and neural network repair in different animal models. Special designed electrodes for in vitro, ex vitro, and animal brains of rats and mice. The system must include a wireless 2100 data acquisition system, which is complete with receiver, USB interface board, and software package. The system must be able to be connected to a computer or laptop via USB 2.0 High Speed and be controlled from MC_Rack or custom programs. It must be compatible with all W2100-headstages. The Headstage has an additional circuit board for wireless optogenetic stimulation via LED or electrical stimulation. This gives the researcher the ability to apply the cell type specific stimulation method of optogenetics to study neural circuit and specific regulation of particular neuron populations. Must have pre- and filter amplifier with integrated data acquisition and analog-digital converter - Gain and bandwidth adjustable via software - Direct access to each electrode for stimulation via internal stimulus generator. - Control of stimulator via the included data acquisition software MC_Rack - 3 independent stimulus generators - Current stimulation at max. +/-1 mA - Voltage stimulation at max. +/-10 V - Sampling rate max. 50 kHz per channel - Integrated heating element (20 , PT 100 sensor) - With installed metal plate for fixing perfusion equipment A system is required that is controlled by a PC computer and has a data acquisition/analysis software package for automatic data collection and analysis. Interface board with signal processor for real-time signal detection and feedback. Includes various in-/outputs: - 4x Digital Out: Interface for output bit 0-3 of the 16-bit digital input / output channels (Lemo connector) - 4x Digital In for synchronization with other instruments (bit 0-3) (Lemo connector) - Digital IN / OUT: Interface for 16-bit digital input / output channels. Generates or accepts TTL-pulses. - 1x Stereo Out: Possibility to export 2 channels (e.g on an oscilloscope or headphones making the signals audible) - 2x Analog IN: Interface for 2 additional analog inputs (channel 1 and 2) (Lemo connector) - Analog IN: 8-channel Analog input (channel 1-8) 1 x TC02: 2-channel temperature controller for biological samples - Set-point temperature reached fast within 30 seconds to 5 minutes - Control temperature range from ambient temperature to +50 °C - Precision controller using PI characteristics Software with USB interface that controls the temperature. - Heatable perfusion cannula with temperature sensor - Peristaltic perfusion system with one inlet and one drain pump, which is necessary for the study of drug effects and other environmental manipulations. - Controlled by software or touch pad - Flow rate: 0 - 30 ml/min Must include an inverted microscope that is compatible with the MEA system for accurate recording and for capture images for morphological and functional analysis. The fluorescence capability must enable identification of specific labeled cells for recordings. The purpose of this synopsis is to gain knowledge of potential qualified sources and their size classification (large business, small business, 8(a), SDVOSB, etc.), relative to NAICS code 423450 (size standard 200 employees). Responses to this synopsis will be used by the Government to make appropriate acquisition decisions. Based on responses to this synopsis, the Government may issue a RFQ. Term of Contract/Delivery Period Date of award + 90 days Type of Contract Firm Fixed Price This notice is not a request for competitive proposals, however; any responsible source who believes it is capable of meeting the requirement may submit a capability statement to the contracting office no later than Tuesday, April 4, 2017 12:00 Noon, EST. Interest/capability statements may be sent to Linda Buccigrossi at
[email protected] and should include company name, address, point of contact, business size, and product information. Pricing may be submitted for market research purposes since quotes are not required since this notice is to assist the Government in determining sources only. A solicitation is not currently available. If a solicitation is issued, all interested parties must respond to that solicitation announcement separately from the responses to this announcement. *No telephone responses will be accepted.