This is NOT a solicitation for proposals, proposal abstracts, or quotations. This Sources Sought is issued for information and planning purposes only as part of USDA ARS market research and does not itself constitute an RFQ. The detailed specification of reagent kits includes: The reagent kits shall enable single cell transcriptional and immune profiling of up to millions of single cells extracted from 32 different tissue sample types. The kits should allow single cell suspensions to be partitioned into thousands or millions of Gel Beads-in-Emulsion (GEMs) with unique barcodes for downstream applications. The assay formulation should be flexible, compatible with the low throughput, standard and high throughput (96-well plate) workflows, with high cell capture efficiency up to 60%. The reagent kits should be compatible for the existing Chromium Controller, for a precisely engineered reagent delivery method that enables > 80,000 of micro-reactions in parallel. The kits should include both reagents and unique dual index oligonucleotides in a 96-well plate form. The kits should include minimal four microfluidics chips, capable of handling 32 tissue samples, with a wide range of eukaryotic cell sizes and cell types. The kits should be versatile with the applications in tagging single cells, individual nuclei, guide RNA, cell surface proteins labeled with antibody-oligonucleotide conjugates, or CRISPR transduced cells. The purchase of reagents should include free and unlimited access to bioinformatic pipelines and visualization software tools for end users, both novice and expert alike. The reagent kits should be delivered in two (or more) batches, per scientists’ requests. This Sources Sought is only for the purpose of identifying potential sources as part of USDA ARS market research. The Government does not intend to make an award based on responses to this inquiry. This notice does not constitute a commitment by the Government. Responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. All information submitted in response to this announcement is voluntary, and the Government will not pay for information requested nor will it compensate any respondent for any cost incurred in developing information provided to the Government. Small business concerns that believe they possess the capabilities necessary to undertake this work should submit complete documentation of their capabilities to the Contracting Officer. Capability statements shall include the name and telephone of a point of contact having authority and knowledge to discuss their response. The capability statement should include: Verification of your business size SAM reps and certs Any information relevant to this requirement in accordance with the Statement of Work. The government requests that no proprietary, classified, confidential, or sensitive information should be included in the response. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization’s qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. Original Point of Contact All responses to this Sources Sought Notice must be received by August 2, 2023 by 09:00 a.m. eastern time, the specified due date and time in order to be considered. Email responses to Ronnie Roscoe at
[email protected]. Responses will not be returned. Responders are solely responsible for all expenses associated with responding to this Inquiry. Do not submit pricing information in response to this Request.