CareDX Lab Solutions

The Centers for Disease Control and Prevention intends to award a Justification For Other Than Full and Open firm fixed price purchase order to CareDx Lab Solutions . The AlloSeq Tx (ASTX17.1 (96) -A-RUO kits allow the interrogation of HLA genotyping (Human Leucocyte Antigen genotyping) on Next-Generation Sequencing platform for The CDC Office of Science (OS), Office of Genomics and Precision Public Health (OGPPH) CDC Funding Integrating Human Genomics into Applied Research and Public Health Surveillance awarded project “Enhancing hemophilia inhibitor risk prediction using genetic risk prediction models in a diverse patient population funding,” The next- generation in genetic matching is provided with the AlloSeq Tx kit utilizing an unique hybrid capture technology. This technology is only available and compatible with the existing Illumina MiSeq platform in our laboratory. AlloSeq Tx leverages Nextera Flex for Enrichment hybrid capture technology from Illumina Inc. to enrich the genes of interest from a whole genome library preparation. The use of hybrid capture technology, as opposed to traditional long-range PCR techniques enables the flexibility of variable gene-sequence content without the need for workflow changes. No other company manufactures or sells this product. Due to the specific, unique and proprietary of the The AlloSeq Tx (ASTX17.1 (96) -A-RUO kits for the interrogation of HLA genotyping (Human Leucocyte Antigen genotyping) on Next-Generation Sequencing platform no other product can be compared and or used with the existing Illumina MiSeq platform currently in use in the laboratory for the specific NGS currently conducted in the laboratory as part of our Office of Genomics and Precision Public Health (OGPPH) CDC Funding Integrating Human Genomics into Applied Research and Public Health Surveillance awarded project . This contract action is for supplies or services for which the Government intends to solicit and negotiate with only one source under the authority of 6.302-1 and 10 U.S.C. 2304(c)(1). Interested persons may identify their interest and capability to respond to the requirement or submit proposals/quote. This notice of intent is not a request for competitive quotations; however, all quotations/responses received within fifteen (15) days of the issuance of this notice will be considered by the government. A determination by the government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the government. Information received will normally be considered solely for the purpose of determining whether to conduct a competitive procurement. Any quotation/response should be emailed to contract specialist at [email protected] by COB 1, June, 2022.