Description
The National Institute on Aging, IRP, intends to negotiate and award a purchase order ona noncompetitive basis with Golden Helix, Inc., 716 S 20th Avenue, Suite 102, Bozeman, MT 59718 for six Helix Tree Software licenses, on site training (6 people-6 days), and statistical genetics consulting . HelixTree is a subject-specific, recursive partitioning-based software product that facilitates the relating of genes and environmental factors to drug outcomes. HelixTree has the ability to relate thousands of interacting genes and environmental factors to clinical outcomes. This presents a novel solution that is much more advanced than the standard single gene finding approach of today. HelixTree Genetics Analysis Software helps unravel complex relationships between genetic, clinical and environmental factors and disease status and drug safety & efficacy. It can handle the growing size and complexity of data sets generated in gene discovery, pharmacogenetics, epidemiology studies and post market surveillance. It directly imports data from a variety of source files such as Excel, SAS, SPSS, S-Plus and more. It also exports the generated results from analyses into these formats. HelixTree, an Affymetrix GeneChip-compatible™ application, also directly imports data from Affymetrix’ GeneChip Mapping 10K 50K and soon 100K and 500K arrays, and has powerful features for dealing with the complexity of large datasets. HelixTree has powerful scripting features based on Python, and the capability to interact with R and S-PLUS software directly within the GUI or a Python shell. The software incorporates a sophisticated FIRM based recursive partitioning data mining engine and advanced genetics analysis features for analyzing SNP data. Golden Helix is the only known source that can supply this software based on a market search. The North American Industry Classification (NAICS) code is 334611 and the size standard is 500. This acquisition is being conducted under Simplified Acquisition procedures and is exempt from the requirement of FAR Part 6, Competition Requirement. This notice of intent is not a request for competitive proposals. Interested parties may identify their interest and capabilities in response to this notice and is solely within the discretion of the government. Comments to this announcement, referencing synopsis Number LPCPSC0634 may be submitted to NIA, 5600 Nathan Shock Drive, GRC Bldg., Room 1E08, Baltimore, MD 21224, Attention: Pat Meise.