e-Vape Self-Administration Inhalation Chamber System For Mice

This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Federal Acquisition Regulation (FAR) Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; Quotes are being requested and a written solicitation will not be issued. The solicitation number is 75N95020P00551 and the solicitation is issued as request for quotation (RFQ) . This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13—Simplified Acquisition Procedures; and FAR Part 12—Acquisition of Commercial Items and is not expected to exceed the simplified acquisition threshold. Humans self-administer nicotine, a key substance contained in tobacco products, by inhaling smokes or vapor (i.e. aerosol). To investigate the neurobiological mechanisms of nicotine self-administration, The National Institute on Drug Abuse (NIDA) Intramural Research Program (IRP) requires a device that facilitates a study of nicotine self-administration via the inhalation route in rodents, a method that mimics how humans self-administer nicotine. The Neurocircuitry of Motivation Section (NMS) aims to understand neural circuits that mediate compulsive behaviors such as drug-taking and drug-seeking behaviors. NMS uses rodent models to achieve this goal. The intravenous administration method has been used extensively to induce drug self-administration behavior. However, humans do not self-administer nicotine through the intravenous route, but the inhalation route. To mimic human administration method, NIDA requires a device that enables its subjects to self-administer nicotine via the inhalation method and to perform operant conditioning procedures. The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2020-06, dated 05-06-2020. NAICS Code : The North American Industry Classification System (NAICS) code is 334519, Analytical Laboratory Instrument Manufacturing. The small business size standard is 500 employees. This requirement is a total small business set-aside . Only those socio-economic business concerns that meet the NAICS code size standard will be considered for the award. Line Items: Through this procurement NIDA anticipates a single award, firm fixed price purchase order for the e-Vape self-administration inhalation chamber system for mice and component parts as described in Attachment 1 – Purchase Description . It is anticipated that the warranty and support services shall consist of a 12-month Base Period, which will begin upon receipt of the items. Below is a table that contains the line item number and description of the requirement for the anticipated award of the Base Period. Line No. 1 - One (1) e-Vape self-administration inhalation chamber system along with the following component parts: Four (4) self-administration chambers; Eight (8) nose pokes; 8 Behavioral conditioning cue-lights; 4 Vapor generators (one for each chamber); and 2 Hakko 25 (or equivalent) vacuum pumps with HEPA filters. Line No. 2 - Shipping, Delivery, and Installation. PLEASE REFER TO THE ATTACHMENTS FOR THE ENTIRE COMBINED SYNOPSIS /SOLICITATION DOCUMENTS, INSTRUCTIONS AND SOLICITATION ATTACHMENTS. Questions and requests for clarification should be submitted electronically to the Contracting Officer, Josh Lazarus at [email protected] on or before 3:00 pm September 8, 2020 Eastern Standard Time . Any questions or request for clarification must include the combined synopsis/solicitation 75N95020P00551 and the Title in the Subject Line. The response to the combined synopsis/solicitation is due no later than September 9, 2020 at 3:00 P.M. Eastern Standard Time . Offers submitted after the deadline may not be considered. The response should be submitted in a searchable electronic format to the Contracting Officer, Josh Lazarus at [email protected]. Electronic submittals must include the combined synopsis/solicitation 75N95020P00551 and the Title in the Subject Line.